Acni Derm Retinol Active Serum

Acne Range

Acne Range · CCFT1089 · 72-Hour Study

Sebum Control, Erythema Reduction, and Barrier Protection — 72-Hour Evaluation

Acni Derm Retinol Active Serum is the most comprehensively instrumented study in the SkinQ Rx portfolio — evaluated across four instruments simultaneously. Tested on oily and sensitive skin covering the full Fitzpatrick I–VI spectrum.

−18.2% Sebum at 1 hr

−16% Erythema at 48 hr

+16% Barrier function

+51% Hydration at 30 min

Subjects

N=32

Protocol

CCFT1089

Duration

72 hours

Skin Type

Oily & sensitive · Fitzpatrick I–VI

Key Outcomes

Clinically Measured Results — 4 Instruments

Sebumeter

−18.2%

Sebum reduction

at 1 hour · 78.63→64.28 µg/cm²

Mexameter

−16%

Erythema reduction

at 48 hours · peak reduction

Tewameter

+16%

Barrier function (TEWL)

at 24 hours · sustained at 48 hr

Corneometer

+51%

Hydration improvement

at 30 minutes

Erythema Reduction Over 72 Hours (Mexameter)

Clinical Summary

Study Overview

Objective

Evaluate 72-hour moisturisation activity and sebum control (primary). Secondary: barrier function (TEWL), erythema reduction, and safety and tolerability on oily and sensitive skin.

Methodology

Open-label dermatologist-led study. N=32 subjects, oily and sensitive skin, Fitzpatrick I–VI. Four instruments simultaneously: Corneometer (hydration), Sebumeter (sebum), Tewameter (TEWL/barrier), Mexameter (erythema index). Protocol CCFT1089. Timepoints: Baseline, 30 min, 24 hr, 48 hr, 72 hr. Women of childbearing potential: negative UPT required.

Findings

Sebum reduced −18.2% at 1hr (78.63→64.28 µg/cm²). Hydration increased +51% at 30 min. Barrier improved +16% at 24 hr, sustained at 48 hr. Erythema peaked at −16% reduction at 48 hr. All four metrics showed clinically meaningful improvement. 0 adverse events.

Study Design

Protocol and Parameters

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Sample Size

N=32

Oily & sensitive skin · 18–45 years

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Skin Profile

Oily & sensitive

Fitzpatrick I–VI (all types)

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Duration

72 hours

Baseline, 30 min, 24 hr, 48 hr, 72 hr

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Protocol

CCFT1089

Jan 2026

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Instruments

4 instruments

Corneometer · Sebumeter · Tewameter · Mexameter

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Laboratory

CCFT Laboratories

Meerut · ISO 9001:2015 · OECD Compliant

Safety & Tolerability

Adverse Event Profile

0 Adverse Events

0 AE — full panel of 32 subjects reported zero side effects.
Tested on oily AND sensitive skin — most demanding skin profile in the study set.
Evaluated across Fitzpatrick I–VI, confirming tolerability across the full skin tone spectrum.
No discontinuations. Full 72-hour study completed by all subjects.

Sebum Control, Erythema Reduction, and Barrier Protection — 72-Hour Evaluation

Clinically Measured Results — 4 Instruments

Study Overview

Protocol and Parameters

Adverse Event Profile

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